Do not use uncontrolled medicines during pregnancy! May increase risk of disability in children

prof. Dr. Mustafa Başbuğ drew attention to the risks of unconscious drug use. Referring to the study published in the August 2022 issue of the American Journal of Obstetrics and Gynecology, Prof. Dr. Mustafa Başbuğ said, “We examined how many of the women living in the United States were exposed to drugs that cause disability during may cause pregnancy or cause problems in the child. As a result, it was revealed that at least 1 in 16 pregnant women were exposed unknowingly or out of necessity. This increases the risk of disability in children,” he said.


Stating that drugs are divided into risk categories according to previous observational studies in terms of the risks of causing disability, Prof. Dr. Mustafa Başbuğ said: “In addition to the substance contained in the drug, factors such as the week of pregnancy, the duration of the drug and whether the drug reaches the fetus are also important in the disabling effect.” Prof. Dr. Başbuğ continued his words as follows:

“Because the fetal organ development takes place, the first three months of pregnancy are more important. Some medications used in the first trimester carry a greater risk of injury. Therefore, the drugs used in the first three months, even if they are vitamins, should be used by asking the obstetrician and, if necessary, the perinatologist. A woman who is known to be pregnant should not just use drugs. Because mandatory resources are used according to risk groups A, B, C, D and X. For example; Some drugs used in epilepsy diseases are included in group D. Although drugs in this group pose a certain risk to children, the mother must use them. Otherwise, there is a risk of death from seizures in the mother. Therefore, in our choice of drugs in epileptic pregnant women, we prefer drugs that cause the least harm to the baby. Therefore, it is very important to determine in advance the risk group of the drug to be used during pregnancy.


“As important as predetermining the disability risk group of the drug to be used during pregnancy is the inclusion of the drug,” said Prof. Dr. Başbuğ, continuing his words as follows:

“An oral drug is not harmful if it is not absorbed from the stomach. For example, since the drugs used in the treatment of diarrhea are not absorbed, they will not harm the child. But if you administer the same drug intravenously, there is a greater chance that the drug will reach the child.”


Regarding the use of antibiotics during pregnancy, one of the most curious topics, Prof. Başbuğ gave the following information:

“For the use of antibiotics during pregnancy, we can say that especially drugs that cross the placenta and have potentially teratogenic effects cause fetal disabilities. In this context, some antibiotics can be given with the condition of safe use, others cannot. Therefore, attention should be paid to the teratogenic effect potential of antibiotics, that they do not cross the placenta, that they do not reach high doses and that the gestational week.

Recalling that women who have chronic diseases and become pregnant have certain medications that they have to take on a routine basis, Prof. Dr. Mustafa Başbuğ said: “A healthy baby can be born with the cooperation of doctors who monitor and will monitor the disease during the pregnancy.”


Yeditepe University Kozyatağı Hospital Gynecology Obstetrics and Perinatology specialist Prof. Dr. Mustafa Başbuğ said the following on this subject:

“Even when giving vitamins it is necessary to be very careful. Because the long-term damage of the additive in vitamin medicines can occur in children. While we’ve talked about congenital disabilities so far, it’s worth noting that some diseases show up late. For example, in some types of cancer, vaginal adenosis in girls aged 8 or 10 can be seen as the effect of a drug used by pregnant women. Diseases related to drug use can not appear immediately after birth, but within 6 months and 1 year. Therefore, the patient should not take any drug without obtaining the patient’s opinion, and should use the appropriate drugs after the advice of the obstetrician and gynecologist and, if necessary, the perinatologist.

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