Memories change: 5 different types of diabetes will be defined

The ‘EndoBridge 2022 Congress’, held this year for the 10th time and bringing together the world’s foremost endocrinology and metabolism experts from 36 countries as the ‘bridge of the hormone world’, took place in Antalya from 20-23 October. Congress president Prof. Dr. Okan Bülent Yıldız said that one of the main topics of the congress this year is the ‘reclassification of diabetes’. The medical world will soon define diabetes patients not only as type 1 and type 2 diabetes, but also with 5 different types of diabetes, and treatments will be reformed accordingly. Prof. Dr. Yıldız has made important statements about this new development, which offers personalized treatments for diabetes rather than standard treatment for each patient.


Prof. Dr Yıldız stated that they reviewed the latest advances in the redefinition, new types and treatment of diabetes at this year’s EndoBridge meeting, saying: “Today, diabetes is basically classified as type 1 and type 2 diabetes.The number of people diagnosed with diabetes in the world is more than 500 million.The number of people with prediabetes or hidden sugar, which we call pre-diabetes, is about 500 million.That’s why we know that more than 1 billion people have problems with sugar elevation. One of the confusing issues here is that using type 1 or type 2 in the diabetes classification is no longer enough. Because we know that some patients in the same class, for example, type 2 diabetes patients, may show different clinical features. is the use of 5 typing in diabetes classification is now on the agenda.New studies show that our practice of personalized, predictive and preventive medicine is easier this way. will settle down,” he said.


Noting that diabetes occurs with different mechanisms in each patient, Prof. Dr Yıldız said: “For example, we define diabetes as type 1 diabetes, which we know as autoimmune causes, when the body’s immune system attacks the beta cells in the pancreas. accepts and attacks that make insulin as foreign It usually starts in childhood or young age This is the main mechanism of this type Now we are talking about the type One of them is diabetes, which develops with severe insulin deficiency The biggest problem here is the inability to make enough insulin. But the mechanism is not related to the immune system. There is also insulin resistance in the third type. Here beta cells in the pancreas can actually make insulin, but “This insulin secretion is not sufficient on tissue and organ level. The fourth type is associated with obesity The fifth is mild diabetes associated with aging. Why is it necessary to use such new 5 different classes? Because their clinical development differs from each other,” he said.


Noting that this topic will be more on the agenda of the scientific world in the coming years, Prof. Dr. Yıldız continued his words as follows:

“By identifying diabetes at an earlier stage with these new types, it will be possible to plan ‘personalized’ treatments for each type, to manage the specific risks of each type at an earlier stage, and to improve the treatment methods we use. will vary according to these subtypes of diabetes Insulin “It will become more important to get it under control in patients whose resistance is severe. Both the appointments to be made in the diet and the lifestyle changes will occur.”


Explaining that there will be differences in the drugs that will be used in patients with the new type of diabetes, Prof. Dr. Okan Bülent Yıldız says: “For example, we know that many patients with type 2 diabetes are taking similar drugs, but in fact they know We know that not all of these drugs have the same effect in every patient. Because the underlying cause is different. , obesity-related diabetes will be milder today, just with weight management and sugar control. At this point we will underline that it is wrong to have a or use more drugs unnecessarily without weight control. We have a very wide range for the treatment of diabetes. As the clinical differences between these new typologies are better understood, these treatment options available to us will be individualized. in particular, we will be able to position these more accurately and effectively s are collected, and especially as the use of new characterizations increases, it will be possible to predict which complication, such as diabetes-related blindness or kidney damage, will develop more quickly or more in patients.” use theirs.

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