Brain and Nerve Surgery Specialist Assoc. Dr Timur Yıldırım stated that Parkinson’s disease is a disease that currently has no cure, but with the development of technology they have taken the disease to a very advanced level. associate Dr Timur Yıldırım, “Parkinson’s disease is characterized by altered activity in the nuclei in the deep brain regions and deep degeneration of special dopaminergic neurons in this region. Clinical manifestations in Parkinson’s disease are characterized by motor and non-motor symptoms. motor disorders; tremors, stiffness, slowness of movement and standing posture disorders. Mood swings, cognitive impairment, sleep disturbance, olfactory and autonomic disturbances, gastrointestinal symptoms, visual hallucinations and other neuropsychiatric disorders are among the non-motor symptoms.
“DBS is the most common surgical treatment for Parkinson’s disease”
Timur Yıldırım noted that drug treatments are one of the main options in the treatment of Parkinson’s disease and that surgical treatments come into play when the response to drug treatment declines for various reasons. the motor symptoms of Parkinson’s disease. Surgical treatment options are also included to improve the quality of life of patients who are resistant to drug treatments. Satisfactory results are obtained with this treatment. There are 2 basic stereotactic methods in the surgical treatment of Parkinson’s disease. The first of these is the onset of a unilateral lesion; The second is DBS. Today, DBS is the most common surgical treatment for Parkinson’s disease. “This treatment strategy is typically reserved for bradykinesia, stiffness and tremor in patients who no longer respond predictably to medication or suffer from drug-induced dyskinesia.”
“DBS operation takes a few hours”
Yıldırım explained that DBS is the process of placing conductive parts called electrodes that transmit electrical current into the movement-related areas of the brain and stimulate the brain through a brain battery connected to them, Yıldırım said: “The brain battery is an electronic device that aims to control the areas of the brain that are going to work overtime due to a lack of dopamine.DBS surgery takes several hours.The patient is awake most of this time.Many patients are affected on both sides of the brain. an electrode is placed The skull is secured with a frame so that the electrode can be placed correctly during surgery A hole is drilled on both sides of the skull where the electrode can be inserted Then the cables connected to both electrodes are placed under passed through the skin and connected to a device called a neurostimulator, which is placed under the skin in the chest is placed.
“The first 3-4 years of Parkinson’s disease are not suitable for DBS”
Stressing that patient selection is one of the most important factors influencing the outcome of surgical treatment for Parkinson’s disease, Yıldırım said: “The first 3-4 years of Parkinson’s disease are not suitable for DBS. Because in this period there is usually a good response of drugs, and also some other neurodegenerative diseases can start with the Parkinson’s disease findings in the early period. However, surgery of late or very advanced patients with a reduced response to the drug also does not give good results. In addition, patients with advanced age (70 years and older), moderate or advanced dementia, and primary psychosis are not eligible for DBS.
Noting that there have been many advances in technology used for surgical management since the first DBS surgeries, Yıldırım said: “The internal batteries used to charge the stimulation have become more efficient and can now be delivered through the skin. charged, reducing the number of surgeries the patient has to undergo to replace the battery Newer versions of DBS components are MR compatible, giving patients and their doctors more flexibility in diagnosing and treating other conditions Parkinson’s is currently a incurable disease, but the benefits of surgery are obvious.It achieves the regression of the disease, equal to the evolution of years. In particular, there is improvement in movements, as well as a decrease in the stiffness and tremors of the patients.